Compound Q&A
How is 4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone (CAS: 160707-69-7) typically synthesized?
Answer
![4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone](https://static.chemtradehub.com/structs/160/160707-69-7-1e15.webp "4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone")
4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone (CAS: 160707-69-7) is synthesized by a multistep process involving the condensation of 2-(hydroxymethyl)-1,3-oxathiolane with 4-amino-1-(2-nitrophenyl)-2(1H)-pyrimidinone, followed by reduction and purification steps. The reaction is typically performed under mild conditions using appropriate solvents and catalysts to achieve good yields and high selectivity.
About
CAS No
160707-69-7
English Name
4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone
Molecular Formula
C8H11N3O3S
Molecular Weight
229.26 g/mol
SMILES
C1C(SC(O1)CO)N2C=CC(=NC2=O)N
InChIKey
RYMCFYKJDVMSIR-RNFRBKRXSA-N
Last Updated: 2026-01-04 19:14
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