Compound Q&A

How is 3-{4-[4-(Chlorosulfonyl)phenyl]-5-methyl-1,2-oxazol-3-yl}benzenesulfonyl chloride (CAS: 1373038-63-1) typically synthesized?

Answer

3-{4-[4-(Chlorosulfonyl)phenyl]-5-methyl-1,2-oxazol-3-yl}benzenesulfonyl chloride
3-{4-[4-(Chlorosulfonyl)phenyl]-5-methyl-1,2-oxazol-3-yl}benzenesulfonyl chloride is synthesized through a multi-step process, often involving the condensation of a 4-chlorosulfonylphenyl derivative with a 5-methyl-1,2-oxazol-3-carboxylic acid compound. The reaction typically requires mild to moderate temperatures and is catalyzed by common reagents like sulfuric acid. The overall yield is generally between 60-80%, depending on the purity of the starting materials and the optimization of reaction conditions.

About

English Name 3-{4-[4-(Chlorosulfonyl)phenyl]-5-methyl-1,2-oxazol-3-yl}benzenesulfonyl chloride
Molecular Formula C16H11Cl2NO5S2
Molecular Weight 432.31 g/mol
SMILES Cc1c(c(no1)c2cccc(c2)S(=O)(=O)Cl)c3ccc(cc3)S(=O)(=O)Cl
InChIKey KDDCVZQQYUBTRK-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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