Compound Q&A

How is 3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0) typically synthesized?

Answer

3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid
3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0) is typically synthesized via a multi-step process involving alkylation, acylation, and fluorination reactions. Key steps include the protection of the amino group, followed by the introduction of the fluorophenyl group and the (2-methyl-2-propanyl)oxy carbonyl group. Common catalysts include anhydrous sodium carbonate and triphenylphosphine, with a yield of around 70-80%.

About

English Name 3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid
Molecular Formula C14H18FNO4
Molecular Weight 283.3 g/mol
SMILES CC(C)(C)OC(=O)NC(CC(=O)O)C1=CC(=CC=C1)F
InChIKey IQPQPXUDXQDVMK-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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