3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid(CAS: 284493-59-0)

3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0) is a crystalline white powder with a molecular weight of approximately 312.29 g/mol. It has a low solubility in water (0.1 g/L at 25°C), and is more soluble in organic solvents like methanol and dichloromethane. Chemically, it is relatively stable but can react with strong bases to form salts. It is also sensitive to acid-hydrolysis. Reactivity varies depending on the environment, but it generally requires mild conditions to avoid degradation.

3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0) is typically synthesized via a multi-step process involving alkylation, acylation, and fluorination reactions. Key steps include the protection of the amino group, followed by the introduction of the fluorophenyl group and the (2-methyl-2-propanyl)oxy carbonyl group. Common catalysts include anhydrous sodium carbonate and triphenylphosphine, with a yield of around 70-80%.

3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0) is primarily used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It may also find applications in polymer chemistry for the development of novel materials and in the manufacturing of sensors due to its unique chemical properties. Its use in semiconductors is less common but still explored for specialized applications.

When handling 3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 284493-59-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work in a well-ventilated area and use a fume hood to minimize exposure to dust and aerosols. Spills should be cleaned up immediately with appropriate absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for specific handling and disposal instructions.