Compound Q&A
How is Benzyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate (CAS: 77497-96-2) typically synthesized?
Answer
Benzyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate is typically synthesized by condensation of benzaldehyde and 3-aminomethylisoquinoline in the presence of a strong base like sodium hydride. The reaction is carried out in an anhydrous solvent such as N,N-dimethylformamide (DMF) at low temperatures. The yield of the product is around 70-80%, and the reaction is known to have good selectivity.
About
CAS No
77497-96-2
English Name
Benzyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate
Molecular Formula
C17H17NO2
Molecular Weight
267.33 g/mol
SMILES
C1C(NCC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3
InChIKey
CAKWIRNQEKMHOR-INIZCTEOSA-N
Last Updated: 2026-01-02 00:31
