Compound Q&A

How is 1,5-Di-O-phosphono-D-ribofuranose (CAS: 14689-84-0) typically synthesized?

Answer

1,5-Di-O-phosphono-D-ribofuranose
1,5-Di-O-phosphono-D-ribofuranose is typically synthesized through the phosphorolysis of D-ribofuranose with phosphorus oxychloride or phosphorus pentoxide. The reaction involves a nucleophilic substitution at the 1 and 5 positions, yielding the desired compound with high selectivity and good yield.

About

CAS No 14689-84-0
English Name 1,5-Di-O-phosphono-D-ribofuranose
Molecular Formula C5H12O11P2
Molecular Weight 310.09 g/mol
SMILES C(C1C(C(C(O1)OP(=O)(O)O)O)O)OP(=O)(O)O
InChIKey AAAFZMYJJHWUPN-SOOFDHNKSA-N
Last Updated: 2026-01-02 00:31

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