Compound Q&A

How is 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione (CAS: 77-41-8) typically synthesized?

Answer

1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione
1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione (CAS: 77-41-8) is typically synthesized through a condensation reaction between phenylacetic acid and methyl acetoacetate, using an appropriate base such as potassium carbonate as a catalyst. The reaction is carried out in a solvent like acetonitrile at an elevated temperature to achieve good yield and selectivity.

About

CAS No 77-41-8
English Name 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione
Molecular Formula C12H13NO2
Molecular Weight 203.24 g/mol
SMILES CC1(CC(=O)N(C1=O)C)C2=CC=CC=C2
InChIKey AJXPJJZHWIXJCJ-UHFFFAOYSA-N
Last Updated: 2026-01-02 00:31

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