Compound Q&A
How is tert-Butyl ((2-aminopyridin-4-yl)methyl)carbamate (CAS: 474809-21-7) typically synthesized?
Answer
tert-Butyl ((2-aminopyridin-4-yl)methyl)carbamate is commonly synthesized via the reaction of 2-aminopyridine-4-carboxylic acid with tert-butyl isocyanide in the presence of a coupling agent such as 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The reaction proceeds with good yield and selectivity, typically yielding a pure product after column chromatography.
About
CAS No
474809-21-7
English Name
tert-Butyl ((2-aminopyridin-4-yl)methyl)carbamate
Molecular Formula
C11H17N3O2
Molecular Weight
223.28 g/mol
SMILES
CC(C)(C)OC(=O)NCC1=CC(=NC=C1)N
InChIKey
JTKROKSMVFTCKQ-UHFFFAOYSA-N
Last Updated: 2026-01-02 00:31
