Compound Q&A
How is 3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide (CAS: 1373038-59-5) typically synthesized?
Answer
3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide can be synthesized through a multi-step process involving the preparation of an intermediate isoxazole, followed by coupling with a sulfonamide group. Common reagents include N,N'-disulfosuccinimidyl carbonate and various amines. The yield is typically around 70-80%, and the reaction is performed under mild conditions with careful control of pH and temperature.
About
CAS No
1373038-59-5
English Name
3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide
Molecular Formula
C16H15N3O5S2
Molecular Weight
393.45 g/mol
SMILES
CC1=C(C(=NO1)C2=CC(=CC=C2)S(=O)(=O)N)C3=CC=C(C=C3)S(=O)(=O)N
InChIKey
ZTJZYTUGYRMBJV-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:06
