3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide(CAS: 1373038-59-5)

3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide is a solid with a crystalline form. Its molecular weight is approximately 518.58 g/mol. It is slightly soluble in water and organic solvents. The compound exhibits good stability under normal conditions but can react with oxidizing agents. It is an isoxazole derivative, which makes it an interesting candidate for various applications in pharmaceuticals and other industries.

3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide can be synthesized through a multi-step process involving the preparation of an intermediate isoxazole, followed by coupling with a sulfonamide group. Common reagents include N,N'-disulfosuccinimidyl carbonate and various amines. The yield is typically around 70-80%, and the reaction is performed under mild conditions with careful control of pH and temperature.

3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide is primarily used in the pharmaceutical industry due to its potential as an anticancer agent. It is also explored for applications in the development of new materials, such as polymers and sensors, due to its unique chemical properties. Additionally, it has potential uses in the electronics and semiconductor industries.

When handling 3-(5-Methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and oxidizing agents. In case of a spill, immediately clean up the area using appropriate spill cleanup procedures and consult the Safety Data Sheet (SDS) for further guidance. Always ensure the fume hood is used during operations to minimize inhalation risks.