Compound Q&A

How is Acetazolamide EP Impurity A (CAS: 60320-32-3) typically synthesized?

Answer

Acetazolamide EP Impurity A
Acetazolamide EP Impurity A (CAS: 60320-32-3) is synthesized through a multi-step process involving the condensation of acetylacetone and ethyl 2-thiouracil. The reaction is typically catalyzed by anhydrous zinc chloride. The product is isolated by recrystallization from water, yielding a crystalline product with high purity.

About

CAS No 60320-32-3
English Name Acetazolamide EP Impurity A
Molecular Formula C4H4ClN3OS
Molecular Weight 177.62 g/mol
SMILES CC(=O)Nc1nnc(Cl)s1
InChIKey CKUUONNLVFAZNC-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:06

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