Compound Q&A
How is (4S)-4-Fluoro-D-proline (CAS: 131176-02-8) typically synthesized?
Answer
(4S)-4-Fluoro-D-proline can be synthesized via chemical derivatization of D-proline using fluorinating agents such as PFP (pentafluorophenyl trifluoromethanesulfonate) under controlled conditions. Common procedures involve the use of reagents like trifluoromethanesulfonic anhydride to introduce the fluorine substituent, followed by purification and crystallization techniques.
About
CAS No
131176-02-8
English Name
(4S)-4-Fluoro-D-proline
Molecular Formula
C5H8FNO2
Molecular Weight
133.12 g/mol
SMILES
C1C(CNC1C(=O)O)F
InChIKey
ZIWHMENIDGOELV-IUYQGCFVSA-N
Last Updated: 2026-01-01 20:06
