Compound Q&A

How is Ethyl 1-methyl-3-propyl-1H-pyrazole-5-carboxylate (CAS: 133261-07-1) typically synthesized?

Answer

Ethyl 1-methyl-3-propyl-1H-pyrazole-5-carboxylate
Ethyl 1-methyl-3-propyl-1H-pyrazole-5-carboxylate (CAS: 133261-07-1) is synthesized through a multi-step process involving the reaction of ethyl isopropyl ketone with hydrazine hydrate, followed by acylation. Common catalysts include p-toluenesulfonic acid, and the final product can be isolated via recrystallization. This method provides a yield of about 80%.

About

English Name Ethyl 1-methyl-3-propyl-1H-pyrazole-5-carboxylate
Molecular Formula C10H16N2O2
Molecular Weight 196.25 g/mol
SMILES CCCC1=NN(C(=C1)C(=O)OCC)C
InChIKey ZPSRHLWRTVNGSM-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:05

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