Compound Q&A
How is Fmoc-a-Me-Asp(OtBu)-OH (CAS: 1072845-47-6) typically synthesized?
Answer
Fmoc-a-Me-Asp(OtBu)-OH (CAS: 1072845-47-6) is synthesized through the coupling of a protected amino acid and a protected aspartic acid derivative. The synthesis involves the use of HATU as a coupling agent and DIPEA as a base. This method provides high yields and good selectivity, making it a common approach in solid-phase peptide synthesis.
About
CAS No
1072845-47-6
English Name
Fmoc-a-Me-Asp(OtBu)-OH
Molecular Formula
C24H27NO6
Molecular Weight
425.48 g/mol
SMILES
O=C(N[C@](C(=O)O)(CC(=O)OC(C)(C)C)C)OCC1c2ccccc2c2c1cccc2
InChIKey
STBMKQNEFSJOCS-DEOSSOPVSA-N
Last Updated: 2026-01-01 20:05
