Compound Q&A

How is cis-3-Amino-1-methylcyclobutanol hydrochloride (CAS: 1523571-03-0) typically synthesized?

Answer

cis-3-Amino-1-methylcyclobutanol hydrochloride (1:1)
cis-3-Amino-1-methylcyclobutanol hydrochloride is typically synthesized via the reaction of 1-methylcyclobutanone with ammonia in the presence of a catalyst, such as sodium hydroxide. The process involves nucleophilic substitution, and yields about 60-70% of the desired product. Post-synthesis, hydrochloric acid is added to form the hydrochloride salt.

About

English Name cis-3-Amino-1-methylcyclobutanol hydrochloride (1:1)
Molecular Formula C5H12ClNO
Molecular Weight 137.61 g/mol
SMILES C[C@]1(C[C@@H](C1)N)O.Cl
InChIKey SZQSVGZFSOUXPL-JEVYUYNZSA-N
Last Updated: 2026-01-01 20:05

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