Compound Q&A
How is 5-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS: 93185-31-0) typically synthesized?
Answer
5-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is commonly synthesized via the condensation of 2-thiohydantoin with an α-hydroxy aldehyde in the presence of a suitable base. The reaction typically involves a selectivity for the α-position and yields around 85-90%.
About
CAS No
93185-31-0
English Name
5-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
Molecular Formula
C5H6N2O2S
Molecular Weight
158.182 g/mol
SMILES
C1=C(C(=O)NC(=S)N1)CO
InChIKey
ANMAXDCIDVNRHA-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:35
