Compound Q&A
How is 2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid (CAS: 1048919-15-8) typically synthesized?
Answer
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2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid is typically synthesized via amidation of 2-fluorobenzoic acid with (2-methyl-2-propanoyloxy)acetic acid. The reaction is catalyzed by a phosphine-based catalyst and proceeds with good selectivity and yield. The product is purified by recrystallization from a suitable solvent.
About
CAS No
1048919-15-8
English Name
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
Molecular Formula
C12H14FNO4
Molecular Weight
255.24 g/mol
SMILES
CC(C)(C)OC(=O)Nc1cccc(F)c1C(=O)O
InChIKey
ADEVFUGRTWPNPT-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:35
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