2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid(CAS: 1048919-15-8)

2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid is a white crystalline solid with a molecular weight of approximately 322.22 g/mol. It is slightly soluble in water and ethanol. The compound exhibits good reactivity, particularly with nucleophiles. It is stable under normal conditions but should be handled under an inert atmosphere to prevent decomposition.

2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid is typically synthesized via amidation of 2-fluorobenzoic acid with (2-methyl-2-propanoyloxy)acetic acid. The reaction is catalyzed by a phosphine-based catalyst and proceeds with good selectivity and yield. The product is purified by recrystallization from a suitable solvent.

2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid is used in the pharmaceutical industry for the development of certain drugs. It may also find applications in the polymer industry as a monomer or intermediate. Additionally, it could be used in the production of sensors and semiconductors due to its unique chemical properties.

When handling 2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dark place and handled under a fume hood to minimize exposure. In case of spill, it should be cleaned up using appropriate procedures, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and safety information.