Compound Q&A

How is 5-Amino-2-chloro-N-(2,4-dimethylphenyl)benzenesulfonamide (CAS: 71215-81-1) typically synthesized?

Answer

5-Amino-2-chloro-N-(2,4-dimethylphenyl)benzenesulfonamide
5-Amino-2-chloro-N-(2,4-dimethylphenyl)benzenesulfonamide is typically synthesized via a multi-step process involving chlorination of a parent sulfonamide, followed by alkylation and amination. Commonly used catalysts include sulfuric acid, and the overall yield can range from 60% to 70%. The synthesis is performed under mild conditions to ensure high selectivity and purity.

About

CAS No 71215-81-1
English Name 5-Amino-2-chloro-N-(2,4-dimethylphenyl)benzenesulfonamide
Molecular Formula C14H15ClN2O2S
Molecular Weight 310.81 g/mol
SMILES CC1=CC(=C(C=C1)NS(=O)(=O)C2=C(C=CC(=C2)N)Cl)C
InChIKey SOWYLSRVTBKKJE-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34

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