Compound Q&A
How is Ciluprevir (CAS: 300832-84-2) typically synthesized?
Answer
Ciluprevir is synthesized via a multi-step process involving Friedel-Crafts alkylation and subsequent ring-closing metathesis reactions. The key catalysts used include ruthenium-based metathesis catalysts and anhydrous conditions to ensure high yield and selectivity. The overall process yields approximately 85% of the desired product with minimal side products.
About
CAS No
300832-84-2
English Name
Ciluprevir
Molecular Formula
C40H50N6O8S
Molecular Weight
774.9 g/mol
SMILES
CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3)OC)C(=C2)OC4CC5C(=O)NC6(CC6C=CCCCCCC(C(=O)N5C4)NC(=O)OC7CCCC7)C(=O)O
InChIKey
PJZPDFUUXKKDNB-KNINVFKUSA-N
Last Updated: 2026-01-01 15:34
