Compound Q&A
How is 5-Chlorosaligenyl-N,N-diisopropylphosphoramidite (CAS: 1620086-77-2) typically synthesized?
Answer
5-Chlorosaligenyl-N,N-diisopropylphosphoramidite (CAS: 1620086-77-2) is typically synthesized via a multi-step process involving the reaction of chloroacetyl chloride with saligenin, followed by the addition of diisopropyl phosphorochloridite. The reaction is catalyzed by a base such as triethylamine, and the product is isolated through recrystallization to obtain the crystalline form.
About
CAS No
1620086-77-2
English Name
5-Chlorosaligenyl-N,N-diisopropylphosphoramidite
Molecular Formula
C13H19ClNO2P
Molecular Weight
287.72 g/mol
SMILES
Clc1ccc2c(c1)COP(O2)N(C(C)C)C(C)C
InChIKey
ZJPWJYRCWIYHMH-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34
