Compound Q&A

How is 1-(4-Chloro-2-pyridinyl)-1-propanone (CAS: 896139-36-9) typically synthesized?

Answer

1-(4-Chloro-2-pyridinyl)-1-propanone
1-(4-Chloro-2-pyridinyl)-1-propanone (CAS: 896139-36-9) is typically synthesized via an electrophilic aromatic substitution reaction using 4-chloropyridine and a protonating agent like triflic acid. The reaction is performed under mild conditions to achieve good yield and selectivity. Catalysts such as Lewis acids can enhance the reaction efficiency.

About

English Name 1-(4-Chloro-2-pyridinyl)-1-propanone
Molecular Formula C8H8ClNO
Molecular Weight 169.61 g/mol
SMILES CCC(=O)C1=NC=CC(=C1)Cl
InChIKey BYWBPEJZCDHZJO-UHFFFAOYSA-N
Last Updated: 2026-01-01 10:50

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