Compound Q&A

How is Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0) typically synthesized?

Answer

Ethyl tetrahydro-2H-pyran-3-carboxylate
Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0) can be synthesized via the esterification of 3-carboxy-2,3-dihydro-1H-pyrane with ethanol in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction requires gentle heating, and the yield can be as high as 80-90%. This compound is also obtained by reacting 3-carboxy-2,3-dihydro-1H-pyrane with ethyl chloroformate under anhydrous conditions.

About

English Name Ethyl tetrahydro-2H-pyran-3-carboxylate
Molecular Formula C8H14O3
Molecular Weight 158.2 g/mol
SMILES CCOC(=O)C1CCCOC1
InChIKey QWLVUZIISWEWFO-UHFFFAOYSA-N
Last Updated: 2026-01-01 10:50

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