Ethyl tetrahydro-2H-pyran-3-carboxylate(CAS: 118870-83-0)

Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0) is a colorless liquid with a molecular weight of approximately 162.19 g/mol. It has a low viscosity and is slightly soluble in water. It exhibits good reactivity with various nucleophiles and is often used as an intermediate in organic synthesis. It has a melting point of -20°C and a boiling point of 171°C.

Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0) can be synthesized via the esterification of 3-carboxy-2,3-dihydro-1H-pyrane with ethanol in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction requires gentle heating, and the yield can be as high as 80-90%. This compound is also obtained by reacting 3-carboxy-2,3-dihydro-1H-pyrane with ethyl chloroformate under anhydrous conditions.

Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0) is predominantly used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of complex organic molecules and is also utilized in the formulation of certain polymers due to its ability to act as a comonomer. Additionally, it finds applications in the production of sensors and semiconductors.

When handling Ethyl tetrahydro-2H-pyran-3-carboxylate (CAS: 118870-83-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a closed container at room temperature away from moisture and heat sources. In case of a spill, it must be cleaned up immediately using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.