Compound Q&A

How is (3S)-3-Amino-3-(2-methoxyphenyl)propanoic acid (CAS: 720662-28-2) typically synthesized?

Answer

(3S)-3-Amino-3-(2-methoxyphenyl)propanoic acid
(3S)-3-Amino-3-(2-methoxyphenyl)propanoic acid can be synthesized through the condensation of 2-methoxybenzaldehyde and methyl glycinate, followed by hydrogenation and hydrolysis. Commonly, a palladium catalyst is used for hydrogenation, and the reaction is typically carried out in an acidic environment to improve selectivity. The overall yield is around 70-80%.

About

English Name (3S)-3-Amino-3-(2-methoxyphenyl)propanoic acid
Molecular Formula C10H13NO3
Molecular Weight 195.21 g/mol
SMILES COC1=CC=CC=C1C(CC(=O)O)N
InChIKey UAZGIQATDPCZHH-QMMMGPOBSA-N
Last Updated: 2026-01-01 06:12

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