Compound Q&A

How is 3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9) typically synthesized?

Answer

3-Propylisobenzofuran-1(3H)-one
3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9) is typically synthesized via a Friedel-Crafts acylation reaction. Benzofuran is treated with propionyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride, to form the final product. This method provides good yield and selectivity. The reaction is conducted under mild conditions and is suitable for both academic and industrial settings.

About

CAS No 72424-08-9
English Name 3-Propylisobenzofuran-1(3H)-one
Molecular Formula C11H12O2
Molecular Weight 176.21 g/mol
SMILES CCCC1C2=CC=CC=C2C(=O)O1
InChIKey TUIQQXQMQKATFQ-UHFFFAOYSA-N
Last Updated: 2025-12-31 21:15

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