3-Propylisobenzofuran-1(3H)-one(CAS: 72424-08-9)

3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9) is a crystalline solid with a molecular weight of approximately 218.3 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound is moderately reactive under basic conditions and is stable under normal storage conditions. It exhibits good spectroscopic properties, including NMR and IR, which make it useful in analytical chemistry.

3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9) is typically synthesized via a Friedel-Crafts acylation reaction. Benzofuran is treated with propionyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride, to form the final product. This method provides good yield and selectivity. The reaction is conducted under mild conditions and is suitable for both academic and industrial settings.

3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9) is used in various industries. It has applications in pharmaceuticals for synthesizing certain drug intermediates, in polymers for enhancing properties, and in sensors due to its spectroscopic properties. The compound also finds use in semiconductor manufacturing, where its thermal stability and chemical reactivity are beneficial.

When handling 3-Propylisobenzofuran-1(3H)-one (CAS: 72424-08-9), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Proper storage in closed containers away from heat and ignition sources is essential. In case of spills, immediately clean up using appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.