Compound Q&A

How is 2-(4-Morpholinyl)-5-nitrobenzonitrile (CAS: 78252-11-6) typically synthesized?

Answer

2-(4-Morpholinyl)-5-nitrobenzonitrile
2-(4-Morpholinyl)-5-nitrobenzonitrile can be synthesized by first reacting 5-nitrobenzonitrile with morpholine in the presence of a suitable base such as potassium carbonate. The reaction is typically performed in an organic solvent like dimethylformamide (DMF) at room temperature. The final product can be isolated by crystallization from appropriate solvents.

About

CAS No 78252-11-6
English Name 2-(4-Morpholinyl)-5-nitrobenzonitrile
Molecular Formula C11H11N3O3
Molecular Weight 17.03 g/mol
SMILES C1COCCN1C2=C(C=C(C=C2)[N+](=O)[O-])C#N
InChIKey RWMGFZRJYLSGJW-UHFFFAOYSA-N
Last Updated: 2025-12-31 21:15

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