Compound Q&A
How is 5-(tert-Butyl)-1H-indole (CAS: 92462-70-9) typically synthesized?
Answer
5-(tert-Butyl)-1H-indole can be synthesized via the indole synthesis route, where tert-butyl chloride is coupled with indole under basic conditions. Other methods include the Stille coupling reaction involving palladium catalysis. The yield is generally good, and the reaction is selective, making it a popular choice for organic chemists.
About
CAS No
92462-70-9
English Name
5-(tert-Butyl)-1H-indole
Molecular Formula
C12H15N
Molecular Weight
173.26 g/mol
SMILES
CC(C)(C)C1=CC2=C(C=C1)NC=C2
InChIKey
QXJXPMHKYYMECP-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:27
