Compound Q&A

How is 1-(2,5-Dimethylphenyl)piperazine (CAS: 1013-25-8) typically synthesized?

Answer

1-(2,5-Dimethylphenyl)piperazine
1-(2,5-Dimethylphenyl)piperazine can be synthesized via a condensation reaction between 2,5-dimethylphenol and piperazine, facilitated by a strong base like sodium hydride. The reaction gives a high yield of 85-90%, with good selectivity towards the desired product.

About

CAS No 1013-25-8
English Name 1-(2,5-Dimethylphenyl)piperazine
Molecular Formula C12H18N2
Molecular Weight 190.29 g/mol
SMILES CC1=CC(=C(C=C1)C)N2CCNCC2
InChIKey YRIFWVMRUFKWLM-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:27

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