Compound Q&A

Is Natalizumab (CAS: 189261-10-7) safe?

Answer

Natalizumab
Natalizumab (CAS: 189261-10-7) is generally considered safe when used under medical supervision. However, it carries a risk of progressive multifocal leukoencephalopathy (PML), a rare but serious brain infection. Patients must undergo regular monitoring for early signs of PML and other potential adverse effects.

About

English Name Natalizumab
Molecular Formula C46H80N14O16SSe
Molecular Weight 1196.26 g/mol
SMILES CC[C@H](C)[C@@H](C(=N[C@@H](CC(C)C)C(=N[C@@H](C)C(=N[C@@H]([C@@H](C)O)C(=N[C@@H](C)C(=N[C@@H](CC(=N)O)C=O)O)O)O)O)O)NN[C@@H](CCC(=N)O)C(=N[C@@H](C[SeH])C(=O)C(=O)[C@H](CCSC)N=C([C@H](C)NN[C@@H](CC(=N)O)C(=O)O)O)O
InChIKey UVWKUTFXSMNLGZ-IOVPNUEZSA-N
Last Updated: 2025-12-30 13:38

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