Compound Q&A
How is trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 (CAS: 91318-10-4) typically synthesized?
Answer
Trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 is typically synthesized via the Stilbene coupling reaction, using diphenylethyne as the starting material in the presence of a palladium catalyst. The reaction proceeds under mild conditions, yielding a high selectivity for the trans isomer. The overall yield is around 70-80%, depending on the purity of the starting materials and reaction conditions.
About
CAS No
91318-10-4
English Name
trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8
Molecular Formula
C18H12D8O2
Molecular Weight
276.4 g/mol
SMILES
CCC(=C(CC)C1=CC=C(C=C1)O)C2=CC=C(C=C2)O
InChIKey
RGLYKWWBQGJZGM-XWCVKCCGSA-N
Last Updated: 2025-12-29 01:16
