trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8(CAS: 91318-10-4)

Trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 (CAS: 91318-10-4) is a crystalline compound with a molecular weight of approximately 440.5 g/mol. It has low water solubility but is soluble in organic solvents like ethanol and acetone. The compound has moderate reactivity with typical organic reagents and is stable under normal laboratory conditions. It does not readily undergo substitution or addition reactions at ambient temperature.

Trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 is typically synthesized via the Stilbene coupling reaction, using diphenylethyne as the starting material in the presence of a palladium catalyst. The reaction proceeds under mild conditions, yielding a high selectivity for the trans isomer. The overall yield is around 70-80%, depending on the purity of the starting materials and reaction conditions.

Trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 (CAS: 91318-10-4) is primarily used in the pharmaceutical industry for research purposes, including hormone studies. It is also explored in the polymer and sensor industries for its unique structural properties, although its applications are more limited compared to other compounds.

When handling trans-Diethyl-1,1,1',1'-stilbestrol-3,3',5,5'-d8 (CAS: 91318-10-4), it is important to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be handled by carefully collecting and disposing of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.