Compound Q&A
How is Ethyl 4,6-dichloro-5-fluoronicotinate (CAS: 154012-17-6) typically synthesized?
Answer
Ethyl 4,6-dichloro-5-fluoronicotinate (CAS: 154012-17-6) is typically synthesized via a multi-step process involving the preparation of 4,6-dichloro-5-fluoronicotinic acid and its subsequent esterification with ethyl alcohol. This process includes careful control of reaction conditions to achieve high yield and selectivity. Catalysts such as sulfuric acid are often used in the esterification step.
About
CAS No
154012-17-6
English Name
Ethyl 4,6-dichloro-5-fluoronicotinate
Molecular Formula
C8H6Cl2FNO2
Molecular Weight
238.045 g/mol
SMILES
CCOC(=O)C1=CN=C(C(=C1Cl)F)Cl
InChIKey
PJAYGSDXQHYXNZ-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
