Compound Q&A

How is 5-Fluoro-2,4-dimethoxyaniline (CAS: 195136-65-3) typically synthesized?

Answer

5-Fluoro-2,4-dimethoxyaniline
5-Fluoro-2,4-dimethoxyaniline can be synthesized through electrophilic aromatic substitution of 2,4-dimethoxyaniline with fluorine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction typically provides good yield and high selectivity for the fluorination at the meta-position.

About

English Name 5-Fluoro-2,4-dimethoxyaniline
Molecular Formula C8H10FNO2
Molecular Weight 171.17 g/mol
SMILES COC1=CC(=C(C=C1N)F)OC
InChIKey QOIDQMOZTRAYET-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55

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