Compound Q&A
How is 5-Amino-6-methylnicotinic acid (CAS: 91978-75-5) typically synthesized?
Answer
5-Amino-6-methylnicotinic acid is synthesized through the methylation of nicotinic acid followed by the amidation of the resulting methyl derivative. Commonly, this involves the use of methyl iodide and a base such as potassium carbonate in an aprotic solvent like dimethylformamide (DMF). The yield is typically around 70-80%, and the reaction is carried out under mild conditions.
About
CAS No
91978-75-5
English Name
5-Amino-6-methylnicotinic acid
Molecular Formula
C7H8N2O2
Molecular Weight
152.153 g/mol
SMILES
CC1=C(C=C(C=N1)C(=O)O)N
InChIKey
KDQUXBVINRXSSD-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59
