Compound Q&A
How is 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole (CAS: 412923-44-5) typically synthesized?
Answer
2-Bromo-4-(4-fluorophenyl)-1,3-thiazole is typically synthesized via a multistep process involving bromination of 4-(4-fluorophenyl)-1,3-thiazole. Commonly, this involves using bromine in the presence of a Lewis acid catalyst like aluminum chloride. The reaction is carried out in an organic solvent, and purification is achieved by recrystallization.
About
CAS No
412923-44-5
English Name
2-Bromo-4-(4-fluorophenyl)-1,3-thiazole
Molecular Formula
C9H5BrFNS
Molecular Weight
258.11 g/mol
SMILES
Fc1ccc(cc1)c2csc(Br)n2
InChIKey
GSCFEPBWOIFTNA-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59
