Compound Q&A
How is 14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid (CAS: 2097938-44-6) typically synthesized?
Answer
![14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid](https://static.chemtradehub.com/structs/209/2097938-44-6-5fd3.webp "14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid")
14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid can be synthesized through multi-step reactions involving condensation reactions and ring formations. Commonly, it is synthesized by reacting 14-amino-tetradecanoic acid with 2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl chloride using a suitable organic base like triethylamine and a phase transfer catalyst. The overall yield is around 75-80%, and the purity is typically >95%.
About
CAS No
2097938-44-6
English Name
14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid
Molecular Formula
C23H29N3O10
Molecular Weight
507.5 g/mol
SMILES
OC(=O)COCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c21
InChIKey
ZXAUDUQJSKVKNG-UHFFFAOYSA-N
Last Updated: 2025-12-28 06:21
![14-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxatetradecan-1-oic acid — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}