Compound Q&A
How is (2R)-2-methyl-2,3-dihydro-1H-indole (CAS: 22160-13-0) typically synthesized?
Answer
(2R)-2-Methyl-2,3-dihydro-1H-indole can be synthesized via the indole synthesis route using the Meerwein-Ponndorf-Verley (MPV) reduction of indole acetone or through the Corey-Kim indole synthesis. Other methods include the Wittig reaction or the ketimine condensation. These processes generally yield around 70-80% purity and require careful handling of reagents and solvents.
About
CAS No
22160-13-0
English Name
(2R)-2-methyl-2,3-dihydro-1H-indole
Molecular Formula
C9H11N
Molecular Weight
133.194 g/mol
SMILES
CC1CC2=CC=CC=C2N1
InChIKey
QRWRJDVVXAXGBT-SSDOTTSWSA-N
Last Updated: 2025-12-28 06:21
