Compound Q&A
How is 1-(5-Methyl-1,3,4-oxadiazol-2-yl)methanamine (CAS: 125295-22-9) typically synthesized?
Answer
1-(5-Methyl-1,3,4-oxadiazol-2-yl)methanamine can be synthesized via the reaction of methyl isocyanate with 5-methyl-1,3,4-oxadiazole. Commonly, this is achieved using phosgene as a catalyst, leading to a high yield of the desired product. The reaction is performed under anhydrous conditions to enhance selectivity and yield. Proper handling of phosgene is essential to prevent unwanted side reactions.
About
CAS No
125295-22-9
English Name
1-(5-Methyl-1,3,4-oxadiazol-2-yl)methanamine
Molecular Formula
C4H7N3O
Molecular Weight
113.12 g/mol
SMILES
CC1=NN=C(O1)CN
InChIKey
XCCHRWGNGFXIPS-UHFFFAOYSA-N
Last Updated: 2025-12-25 22:28
