Compound Q&A

How is 4-Methyl-1,2-oxazole-3-carboxylic acid (CAS: 215872-46-1) typically synthesized?

Answer

4-Methyl-1,2-oxazole-3-carboxylic acid
4-Methyl-1,2-oxazole-3-carboxylic acid can be synthesized via the condensation of methyl acetoacetate with formaldehyde and subsequent acidification. This reaction is typically catalyzed by an acid, such as sulfuric acid, and proceeds with good selectivity and moderate to high yield.

About

English Name 4-Methyl-1,2-oxazole-3-carboxylic acid
Molecular Formula C5H5NO3
Molecular Weight 127.1 g/mol
SMILES CC1=CON=C1C(=O)O
InChIKey OFLBJRPOLLXDSC-UHFFFAOYSA-N
Last Updated: 2025-12-25 22:28

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