Compound Q&A

How is 1,3-Benzoxazole-6-carbaldehyde (CAS: 865449-97-4) typically synthesized?

Answer

1,3-Benzoxazole-6-carbaldehyde
1,3-Benzoxazole-6-carbaldehyde is often synthesized via the condensation of benzaldehyde and oxazole, or by the alkylation of 1,3-benzoxazine-6-carbonitrile. The reaction typically involves the use of a base like sodium hydroxide to promote deprotonation and subsequent nucleophilic substitution. The yield is generally good, and the product can be purified by recrystallization.

About

English Name 1,3-Benzoxazole-6-carbaldehyde
Molecular Formula C8H5NO2
Molecular Weight 147.13 g/mol
SMILES O=CC1=CC2=C(C=C1)N=CO2
InChIKey AAXBJXNWZVAVDH-UHFFFAOYSA-N
Last Updated: 2025-12-25 22:28

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