Compound Q&A
How is 2'-Deoxy-5'-O-trityluridine (CAS: 14270-73-6) typically synthesized?
Answer
2'-Deoxy-5'-O-trityluridine is synthesized by tritylation of 2'-deoxyuridine. The reaction involves the use of a trityl chloride reagent and is typically carried out under anhydrous conditions. The yield is usually around 70-80% with good selectivity. The reaction is catalyzed by a strong base, such as pyridine or triethylamine.
About
CAS No
14270-73-6
English Name
2'-Deoxy-5'-O-trityluridine
Molecular Formula
C28H26N2O5
Molecular Weight
470.53 g/mol
SMILES
C1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)O
InChIKey
JJJNFNLUKYZAKI-BFLUCZKCSA-N
Last Updated: 2025-12-25 08:48
