Compound Q&A

How is (5Z)-7-(3,5-Dihydroxy-2-{(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl)-5-heptenoic acid (CAS: 54276-17-4) typically synthesized?

Answer

(5Z)-7-(3,5-Dihydroxy-2-{(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl)-5-heptenoic acid
This compound is synthesized through a multistep process involving functional group manipulations and coupling reactions. Commonly, it is prepared using a Suzuki coupling reaction followed by esterification and amidation. Specific catalysts such as palladium(II) chloride and bases like sodium carbonate are used to achieve high selectivity and yield.

About

CAS No 54276-17-4
English Name (5Z)-7-(3,5-Dihydroxy-2-{(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl)-5-heptenoic acid
Molecular Formula C23H29F3O6
Molecular Weight 458.47 g/mol
SMILES O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C[C@@H]1O
InChIKey WWSWYXNVCBLWNZ-MTECWQMOSA-N
Last Updated: 2025-12-25 08:48

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