Compound Q&A

How is Methyl 2-(dimethoxyphosphoryl)propanoate (CAS: 26530-60-9) typically synthesized?

Answer

Methyl 2-(dimethoxyphosphoryl)propanoate
Methyl 2-(dimethoxyphosphoryl)propanoate is synthesized by the phosphorylation of methyl 2-methoxypropanoate with phosphorus oxychloride. The reaction is carried out under anhydrous conditions using a catalyst such as pyridine. The yield of the product is typically around 85%, and the reaction is selective towards the desired phosphorylation product.

About

CAS No 26530-60-9
English Name Methyl 2-(dimethoxyphosphoryl)propanoate
Molecular Formula C6H13O5P
Molecular Weight 196.14 g/mol
SMILES CC(C(=O)OC)P(=O)(OC)OC
InChIKey STYUEUAAPQZSTL-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48

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