How is N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide (CAS: 29110-47-2) typically synthesized?

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide is synthesized via the chlorination of 2-aminophenyl acetamide followed by the carbamimidoylation reaction. The process typically involves the use of thionyl chloride as a chlorinating agent and carbonyldiimidazole (CDI) as the carbamimidoylating agent. The yield is usually around 70-80%, and the reaction is carried out under anhydrous conditions to avoid side reactions.