N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide(CAS: 29110-47-2)

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide is a white crystalline solid with a molecular weight of approximately 331.02 g/mol. It has a low water solubility and is moderately soluble in organic solvents like methanol and acetonitrile. This compound is chemically stable but may react with bases and reduce the pH during storage. It is susceptible to hydrolysis under acidic conditions.

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide is synthesized via the chlorination of 2-aminophenyl acetamide followed by the carbamimidoylation reaction. The process typically involves the use of thionyl chloride as a chlorinating agent and carbonyldiimidazole (CDI) as the carbamimidoylating agent. The yield is usually around 70-80%, and the reaction is carried out under anhydrous conditions to avoid side reactions.

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide is primarily used in the pharmaceutical and agrochemical industries for the production of various active pharmaceutical ingredients (APIs) and herbicides. It is also utilized in the sensor and semiconductor industries for specific applications requiring high purity and stability.

When handling N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed information on handling, storage, and disposal procedures.