Compound Q&A

How is HO-PEG16-OH (CAS: 6812-36-8) typically synthesized?

Answer

HO-PEG16-OH
HO-PEG16-OH is typically synthesized through the reaction of 16-oxido-2-oxo-1,2-ethanediol with ethylene oxide using catalytic amounts of sodium hydroxide. The reaction involves the gradual addition of ethylene oxide to the epoxide group of the starting material, followed by hydrolysis of the resulting ether intermediate to yield the final product.

About

CAS No 6812-36-8
English Name HO-PEG16-OH
Molecular Formula C32H66O17
Molecular Weight 722.863 g/mol
SMILES C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)O
InChIKey DHORSBRLGKJPFC-UHFFFAOYSA-N
Last Updated: 2025-12-25 04:58

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