Compound Q&A
How is 2,5-Difluoro-4-methylbenzonitrile (CAS: 1003708-66-4) typically synthesized?
Answer
2,5-Difluoro-4-methylbenzonitrile (CAS: 1003708-66-4) is typically synthesized via the reaction of 2,5-difluoro-4-methylbenzoyl chloride with sodium cyanide in a polar aprotic solvent. The reaction provides a yield of about 85% to 90% with high selectivity. Commonly used solvents include dimethylformamide or acetonitrile, and the reaction is generally carried out under mild conditions.
About
CAS No
1003708-66-4
English Name
2,5-Difluoro-4-methylbenzonitrile
Molecular Formula
C8H5F2N
Molecular Weight
17.03 g/mol
SMILES
N#CC1=CC(F)=C(C)C=C1F
InChIKey
JPNDTPNCYOHHFX-UHFFFAOYSA-N
Last Updated: 2025-12-25 04:58
