Compound Q&A
How is 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine (CAS: 1323919-64-7) typically synthesized?
Answer
![1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine](https://static.chemtradehub.com/structs/132/1323919-64-7-b33a.webp "1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine")
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine is commonly synthesized via a multi-step process involving the coupling of a pyrazole derivative with 1-methylpiperidine in the presence of a borate ester and a palladium catalyst. The reaction is typically carried out under standard conditions of temperature and pressure with high selectivity and yield.
About
CAS No
1323919-64-7
English Name
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine
Molecular Formula
C15H26BN3O2
Molecular Weight
291.2 g/mol
SMILES
CN1CCC(CC1)n1ncc(c1)B1OC(C(O1)(C)C)(C)C
InChIKey
PRLTVODJPCFDHW-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29
![1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}